Response to Overly grainy negatives. Help. What happened?

I have had lots of fellows (mainly students) that have shown me really grainy pictures that they have achieved using materials and techniques that normally don't give too much grain. I still am puzzled and cannot come up with a logical explanation about how this can happen. Before I start believing in Gremlins, someone should help us all clear up the situation. If anyone has any info on the subject, please let us know more about it. An idea might be mild reticulation (as mentioned above) or other emulsion characteristics change, by chemical or physical causes...

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